Combined MRI-EEG techniques for correlation of anatomy and function in human somatosensory cortex

James P. Boyle; Edward F. Kelly

doi:10.1117/12.174397

1 May 1994 Combined MRI-EEG techniques for correlation of anatomy and function in human somatosensory cortex

James P. Boyle, Edward F. Kelly

Proceedings Volume 2168, Medical Imaging 1994: Physiology and Function from Multidimensional Images; (1994) https://doi.org/10.1117/12.174397
Event: Medical Imaging 1994, 1994, Newport Beach, CA, United States

Abstract

Recent advances in high-resolution EEG imaging methods have made it advantageous to decrease inter-electrode distance to approximately 1 - 2 cm. To take full advantage of this increased recording density, it has become imperative to consider inter-subject anatomical variability and even intra-subject anatomical asymmetry. The present study used anatomical information from MRI to augment functional data obtained through EEG. Specifically, acrylic helmets made for each subject and normally used during EEG were utilized to orient NMR sample tubes filled with a marker medium (H₂O(DOT)Cu₂SO₄) radially from the scalp at selected EEG recording sites during MRI. Using the software package AVS, the MRI data could then be volumetrically 3-D rendered, 3-D isosurface rendered, or arbitrarily sliced. The tubes appeared in the 3-D renderings as pointers from recording sites to underlying cortical anatomy. Our task was simplified by our focus on a limited area of the cortex. The renderings provide subject-specific anatomical templates for mapping of EEG topographic patterns and clearly reveal individual variations of cortical surface topography that are usually unaccounted for in EEG analysis.

Citation Download Citation

James P. Boyle and Edward F. Kelly "Combined MRI-EEG techniques for correlation of anatomy and function in human somatosensory cortex", Proc. SPIE 2168, Medical Imaging 1994: Physiology and Function from Multidimensional Images, (1 May 1994); https://doi.org/10.1117/12.174397

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