Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results

Martin Forrer; Jerome C. Mizeret; Daniel Braichotte; Georges A. Wagnieres; Jean-Francois Savary; Philippe Monnier; Patrice Jichlinski; Hans-Juerg Leisinger M.D.; Hubert van den Bergh

doi:10.1117/12.203434

1 March 1995 Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results

Martin Forrer, Jerome C. Mizeret, Daniel Braichotte, Georges A. Wagnieres, Jean-Francois Savary, Philippe Monnier, Patrice Jichlinski, Hans-Juerg Leisinger M.D., Hubert van den Bergh

Author Affiliations +

Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995) https://doi.org/10.1117/12.203434
Event: Fifth International Photodynamic Association Biennial Meeting, 1994, Amelia Island, FL, United States

Abstract

Clinical results obtained endoscopically with an imaging fluorescence photodetection apparatus based on the use of one excitation wavelength and detection of the fluorescence emission performed in two separate spectral windows are presented. Early cancer photodetection of micro-invasive and in situ carcinoma of the bronchial mucosa after intravenous injection of meso-tetrahydroxyphenylchlorin (m-THPC) was performed during sessions involving photodynamic therapy. Preliminary results are also presented in the context of detecting transitional cell carcinoma of the bladder performed by fluorescence imaging photodetection of protoporphyrin IX (PPIX) following topical application of 5-delta aminolevulinic acid (ALA).

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Martin Forrer, Jerome C. Mizeret, Daniel Braichotte, Georges A. Wagnieres, Jean-Francois Savary, Philippe Monnier, Patrice Jichlinski, Hans-Juerg Leisinger M.D., and Hubert van den Bergh "Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results", Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); https://doi.org/10.1117/12.203434

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