Independent pathway for inclusion complexes of porphyrinoid drugs in tumors: the separation from the lipoprotein pathway in plasma

Joerg G. Moser; Anja Ruebner-Heuermann; Andrea Weitemeyer; Ulrike Michelsen; Dieter Woehrle; Angelika C. Rueck; Wolfgang S. L. Strauss; Dieter Kirsch; Sonja Andrees; Chrs. Schroers

doi:10.1117/12.230980

31 January 1996 Independent pathway for inclusion complexes of porphyrinoid drugs in tumors: the separation from the lipoprotein pathway in plasma

Joerg G. Moser, Anja Ruebner-Heuermann, Andrea Weitemeyer, Ulrike Michelsen, Dieter Woehrle, Angelika C. Rueck, Wolfgang S. L. Strauss, Dieter Kirsch, Sonja Andrees, Chrs. Schroers

Author Affiliations +

Proceedings Volume 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities; (1996) https://doi.org/10.1117/12.230980
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

Phthalocyanines and m-TPPs were substituted with two or three t-butyl phenyl anchor groups to build up inclusion complexes with dimeric (beta) -cyclodextrins. These complexes proved to be stable enough to hinder complexation of the porphyrinoids with plasma lipoproteins and, so, offer an independent pathway to transfer porphyrinoids to photosensitize tumor tissue.

Citation Download Citation

Joerg G. Moser, Anja Ruebner-Heuermann, Andrea Weitemeyer, Ulrike Michelsen, Dieter Woehrle, Angelika C. Rueck, Wolfgang S. L. Strauss, Dieter Kirsch, Sonja Andrees, and Chrs. Schroers "Independent pathway for inclusion complexes of porphyrinoid drugs in tumors: the separation from the lipoprotein pathway in plasma", Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); https://doi.org/10.1117/12.230980

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available