Design of low-energy neutron beams for boron neutron capture synovectomy

Jacquelyn C. Yanch; Ruth E. Shefer; E. Binello

doi:10.1117/12.267911

27 February 1997 Design of low-energy neutron beams for boron neutron capture synovectomy

Jacquelyn C. Yanch, Ruth E. Shefer, E. Binello

Proceedings Volume 2867, International Conference Neutrons in Research and Industry; (1997) https://doi.org/10.1117/12.267911
Event: Fifth International Conference on Applications of Nuclear Techniques: Neutrons in Research and Industry, 1996, Crete, Greece

Abstract

A novel application of the ¹⁰B(n, (alpha) )⁷Li nuclear reaction for the treatment of rheumatoid arthritis is under development. this application, called Boron Neutron Capture Synovectomy (BNCS), is briefly described here and the differences between BNCS and Boron Neutron Capture Therapy (BNCT) are discussed in detail. These differences lead to substantially altered demands on neutron beam design for each therapy application. In this paper the considerations for neutron beam design for the treatment of arthritic joints via BNCS are discussed, and comparisons with the design requirements for BNCT are made. This is followed by a description of potential moderator/reflector assemblies that are calculated to produce intense, high- quality neutron beams based on the ⁷Li(p,n) accelerator- based reactions. Total therapy time and therapeutic ratios are given as a function of both moderator length and boron concentration. Finally, a means of carrying out multi- directional irradiations of arthritic joints is proposed.

Citation Download Citation

Jacquelyn C. Yanch, Ruth E. Shefer, and E. Binello "Design of low-energy neutron beams for boron neutron capture synovectomy", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); https://doi.org/10.1117/12.267911

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