Feasibility study of BNCT of skin melanoma with an accelerator-based neutron source

Stefano Agosteo; P. Colautti; M. G. Corrado; F. d'Errico; Sandra Monti; Marco Silari; R. Tinti; G. Tornielli

doi:10.1117/12.267944

27 February 1997 Feasibility study of BNCT of skin melanoma with an accelerator-based neutron source

Stefano Agosteo, P. Colautti, M. G. Corrado, F. d'Errico, Sandra Monti, Marco Silari, R. Tinti, G. Tornielli

Proceedings Volume 2867, International Conference Neutrons in Research and Industry; (1997) https://doi.org/10.1117/12.267944
Event: Fifth International Conference on Applications of Nuclear Techniques: Neutrons in Research and Industry, 1996, Crete, Greece

Abstract

The feasibility of an accelerator-driven thermal neuron source for Boron Neutron Capture Therapy (BNCT) of skin melanoma is discussed, based on the design of an analogous source for BNCT of the explanted liver. Monte Carlo simulations were performed by introducing some variations in the moderator geometry of that source. Neutrons are generated by 7 MeV deuterons impinging on a thick beryllium target. The neutron moderator consists of a nuclear graphite structure containing a heavy water tank in turn enclosing the beryllium target. The moderator materials were chosen in order to minimize the production of prompt gamma rays. THe requested neutron fluence can be achieved in three hours with a deuteron current in the range of 3-8 mA.

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Stefano Agosteo, P. Colautti, M. G. Corrado, F. d'Errico, Sandra Monti, Marco Silari, R. Tinti, and G. Tornielli "Feasibility study of BNCT of skin melanoma with an accelerator-based neutron source", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); https://doi.org/10.1117/12.267944

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