Sol gel-based fiber optic pH sensor

Sheila A. Grant; Robert S. Glass

doi:10.1117/12.275514

16 June 1997 Sol gel-based fiber optic pH sensor

Sheila A. Grant, Robert S. Glass

Proceedings Volume 2976, Biomedical Sensing, Imaging, and Tracking Technologies II; (1997) https://doi.org/10.1117/12.275514
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

We report here on the development of a sol-gel based fiber optic sensor to monitor local blood pH. These sensors are being developed for invasive medical applications; that is, they will be coaxially threaded through a catheter beyond an occlusion in the vascular system. The fiber optic pH sensor design was based on the immobilization of a pH sensitive dye, seminaphthorhodamine-1 carboxylate, onto the tip or surface of an optical fiber using the sol-gel method. The fiber optic pH sensor was tested in phosphate buffer saline and human whole blood using a miniature fluorimeter system. Linear responses were obtained in blood in the pH range 6.7 to 8.0, which demonstrates potential for use for in vivo sensing.

Citation Download Citation

Sheila A. Grant and Robert S. Glass "Sol gel-based fiber optic pH sensor", Proc. SPIE 2976, Biomedical Sensing, Imaging, and Tracking Technologies II, (16 June 1997); https://doi.org/10.1117/12.275514

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