Description of an improved laser Doppler calibrator

Wiendelt Steenbergen; Frits F. M. de Mul

doi:10.1117/12.348364

17 May 1999 Description of an improved laser Doppler calibrator

Wiendelt Steenbergen, Frits F. M. de Mul

Author Affiliations +

Proceedings Volume 3599, Optical Diagnostics of Biological Fluids IV; (1999) https://doi.org/10.1117/12.348364
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

An improved version of our laser Doppler tester has been developed. The tester contains a tissue phantom made in the form of a thin film. Films with a thickness in the range 20 - 90 micrometer are stacked to reach a total thickness of several millimeters. Motion is realized by rotating discs with a thickness of 20 - 22 micrometer, separated by a static layer of 95 micrometer thickness. The total number of movable layers is 13. The tester contains four phantom stacks, each mimicking a different type of tissue. Since each tissue consists of a stack of thin layers separated by a matching medium, the consequence of a possible mismatch on the photon penetration depth is investigated with the Monte Carlo simulation technique. This leads to a range of refractive indices in which the matching medium must be taken to keep the effect of mismatch below an acceptable level. It appears that for a tissue structure composed of layers with a thickness of 30 micrometer, the refractive index of the matching material should be between 1.50 and 1.54 for a refractive index of the matrix material of the phantom equal to 1.52. Within this range, the effect of mismatch on the probed depth and the total reflection is limited to 2%.

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Wiendelt Steenbergen and Frits F. M. de Mul "Description of an improved laser Doppler calibrator", Proc. SPIE 3599, Optical Diagnostics of Biological Fluids IV, (17 May 1999); https://doi.org/10.1117/12.348364

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