Optical property determination of turbid media using frequency-domain infrared photothermal radiometry

Andreas Mandelis; Lena Nicolaides; Yan Chen; I. Alex Vitkin

doi:10.1117/12.386312

19 May 2000 Optical property determination of turbid media using frequency-domain infrared photothermal radiometry

Andreas Mandelis, Lena Nicolaides, Yan Chen, I. Alex Vitkin

Proceedings Volume 3916, Biomedical Optoacoustics; (2000) https://doi.org/10.1117/12.386312
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Among diffusion methods, photothermal radiometry (PTR) has the ability to penetrate and yield information about an opaque medium well beyond the range of conventional optical imaging. Owing to this ability, pulsed-laser PTR has been extensively used in turbid media such as biological tissue to study the sub-surface deposition of laser radiation, a task which may be difficult or impossible for conventional optical methods due to excessive scattering and absorption. In this work, the optical and thermal properties of tissue- like materials are observed using frequency-domain IR photothermal radiometry. An approximate 3D heat conduction formulation with the use of 1D optical diffusion is developed to derive a turbid frequency-domain PTR model. The agreement in the absorption and transparent scattering coefficients of model phantoms is investigated. The present opto-thermal model for frequency-domain PTR may prove useful for non-contact, non-invasive, in situ measurement of optical properties of tissues and other multiply-scattering media.

Citation Download Citation

Andreas Mandelis, Lena Nicolaides, Yan Chen, and I. Alex Vitkin "Optical property determination of turbid media using frequency-domain infrared photothermal radiometry", Proc. SPIE 3916, Biomedical Optoacoustics, (19 May 2000); https://doi.org/10.1117/12.386312

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