Probing biological processes using a multifunction "molecular radar"

Hui Ma; L. Jin; Chunyang Zhang; Yao Ding; D. Y. Chen

doi:10.1117/12.383344

21 April 2000 Probing biological processes using a multifunction "molecular radar"

Hui Ma, L. Jin, Chunyang Zhang, Yao Ding, D. Y. Chen

Author Affiliations +

Proceedings Volume 3922, Scanning and Force Microscopies for Biomedical Applications II; (2000) https://doi.org/10.1117/12.383344
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Molecular Radar represents techniques capable of probing in real time biological processes in living samples. Compared to biochemistry techniques, MR focuses on spatial and temporal features of the process. It also integrates different types of measurements in order to interrogate a complicated biological system from different perspectives and to reveal correlation among the measured parameters. Based on a two-photon fluorescence microscope, we are developing a MR with fluorescence imaging and fluorescence correlation spectroscopy functions. Using the system, we obtained free calcium ion response in a transmembrane signal transduction study. In a different effort, the system is being used to obtain autofluorescence of elastin in rat aorta.

Citation Download Citation

Hui Ma, L. Jin, Chunyang Zhang, Yao Ding, and D. Y. Chen "Probing biological processes using a multifunction "molecular radar"", Proc. SPIE 3922, Scanning and Force Microscopies for Biomedical Applications II, (21 April 2000); https://doi.org/10.1117/12.383344

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