Short and ultrashort laser pulse induced bubbles on transparent and scattering tissue models

Francisco Pérez-Gutierrez; Rodger Evans; Santiago Camacho-Lopez; Guillermo Aguilar

doi:10.1117/12.701566

21 February 2007 Short and ultrashort laser pulse induced bubbles on transparent and scattering tissue models

Francisco Pérez-Gutierrez, Rodger Evans, Santiago Camacho-Lopez, Guillermo Aguilar

Proceedings Volume 6435, Optical Interactions with Tissue and Cells XVIII; 64350V (2007) https://doi.org/10.1117/12.701566
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Bubble formation is a well identified phenomenon within short (ns) and ultrashort (fs) laser pulses-aqueous media interactions. Bubble formation might be produced by three different mechanisms: (1) optical breakdown, (2) rarefraction wave and (3) overheating of the material. Experiments where transparent and scattering tissue models that mimic biological tissue were irradiated with a Q-switched, 532 nm, 5 nanosecond, Nd:YAG and Ti:sapphire femtosecond laser systems. The type of bubble (transient or permanent) and initial bubble diameter were characterized as a function of time as well as the number of pulses and repetition rate at which they were delivered. Threshold fluence for bubble formation in scattering tissue model was also studied. Two types of bubbles were identified depending on the number of pulses and the repetition rate at which they were delivered: transient (type 1) and permanent (type 2) bubbles. There is an insignificant difference in the fluence required to form a bubble in transparent tissue models regardless of the depth at which the beam was focused; in contrast, for scattering tissue models, the fluence required to form a bubble in deep positions is significantly higher than that of more superficial beam focus positions.

Citation Download Citation

Francisco Pérez-Gutierrez, Rodger Evans, Santiago Camacho-Lopez, and Guillermo Aguilar "Short and ultrashort laser pulse induced bubbles on transparent and scattering tissue models", Proc. SPIE 6435, Optical Interactions with Tissue and Cells XVIII, 64350V (21 February 2007); https://doi.org/10.1117/12.701566

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available