The correlation study of temperature distribution with the immunology response under laser radiation

Yichao Chen; Robert E. Nordquist; Mark F. Naylor; Feng Wu; Hong Liu; Yasvir A. Tesiram; Andrew Abbott; Rheal A. Towner; Wei R. Chen

doi:10.1117/12.763964

28 February 2008 The correlation study of temperature distribution with the immunology response under laser radiation

Yichao Chen, Robert E. Nordquist, Mark F. Naylor, Feng Wu, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, Wei R. Chen

Author Affiliations +

Proceedings Volume 6857, Biophotonics and Immune Responses III; 68570E (2008) https://doi.org/10.1117/12.763964
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

The 3-D, in vivo temperature distributions within tumor-bearing rats were measured using Magnetic Resonance Imaging (MRI) technique. The in vivo thermal distributions of rats were measured using MRI chemical shift of water proton density. DMBA-4 tumor bearing rats are treated using laser photothermal therapy combined with immunoadjuvant under the observation of MRI. The thermal images and the immunological responses were studied and their relationships were investigated. The study of thermal distribution and correlation with the immunological response under laser treatment provided rich information with potential guidance for thermal-immunological therapy.

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Yichao Chen, Robert E. Nordquist, Mark F. Naylor, Feng Wu, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen "The correlation study of temperature distribution with the immunology response under laser radiation", Proc. SPIE 6857, Biophotonics and Immune Responses III, 68570E (28 February 2008); https://doi.org/10.1117/12.763964

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