Interferometric synthetic aperture microscopy: tissue structure inferred by computed imaging techniques

Daniel L. Marks; Tyler S. Ralston; Brynmor J. Davis; P. Scott Carney; Stephen A. Boppart

doi:10.1117/12.763390

22 February 2008 Interferometric synthetic aperture microscopy: tissue structure inferred by computed imaging techniques

Daniel L. Marks, Tyler S. Ralston, Brynmor J. Davis, P. Scott Carney, Stephen A. Boppart

Author Affiliations +

Proceedings Volume 6864, Biomedical Applications of Light Scattering II; 686407 (2008) https://doi.org/10.1117/12.763390
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Interferometric Synthetic Aperture Microscopy (ISAM)¹ is an optical microscopy computed-imaging technique for measuring the optical properties of three-dimensional structures and biological tissues. In this work, the principle of ISAM is reviewed, and its application to imaging tissue properties in various scanning geometries and instrument configurations is explored. The practicality of ISAM is demonstrated by imaging a rat heart and muscle using a real-time implementation of ISAM in conjunction with a clinical cart Optical Coherence Tomography instrument.

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Daniel L. Marks, Tyler S. Ralston, Brynmor J. Davis, P. Scott Carney, and Stephen A. Boppart "Interferometric synthetic aperture microscopy: tissue structure inferred by computed imaging techniques", Proc. SPIE 6864, Biomedical Applications of Light Scattering II, 686407 (22 February 2008); https://doi.org/10.1117/12.763390

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