In-vivo imaging of microcirculation using integrated photoacoustic and optical-coherence microscopy

Li Li; Konstantin I. Maslov; Geng Ku; Lihong V. Wang

doi:10.1117/12.809323

24 February 2009 In-vivo imaging of microcirculation using integrated photoacoustic and optical-coherence microscopy

Li Li, Konstantin I. Maslov, Geng Ku, Lihong V. Wang

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 71770I (2009) https://doi.org/10.1117/12.809323
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Photoacoustic imaging and optical coherence tomography have complementary imaging contrasts. Photoacoustic imaging is sensitive to optical absorption, thus is able to generate detailed maps of deep microvasculature in vivo. Optical coherence tomography exploits the optical scattering contrast, and can provide real-time, micrometer-resolution imaging of tissue. We integrate an optical-resolution photoacoustic microscopy and a spectral-domain optical coherence tomography into a single system. Our preliminary experiments showed that it could be a valuable imaging tool for microcirculation studies in vivo.

Citation Download Citation

Li Li, Konstantin I. Maslov, Geng Ku, and Lihong V. Wang "In-vivo imaging of microcirculation using integrated photoacoustic and optical-coherence microscopy", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770I (24 February 2009); https://doi.org/10.1117/12.809323

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