Hybrid nano plasmonics for integrated biosensor

Chii-Wann Lin; Jun-Haw Lee; Nan-Fu Chiu; Szu-Yuan Lee; Kou-Chen Liu; Feng-Yu Tsai; Chia-Yu Yen; Chun-Nan Lee

doi:10.1117/12.853214

30 November 2009 Hybrid nano plasmonics for integrated biosensor

Chii-Wann Lin, Jun-Haw Lee, Nan-Fu Chiu, Szu-Yuan Lee, Kou-Chen Liu, Feng-Yu Tsai, Chia-Yu Yen, Chun-Nan Lee

Proceedings Volume 7634, Optical Sensors and Biophotonics; 76340O (2009) https://doi.org/10.1117/12.853214
Event: Asia Communications and Photonics, 2009, Shanghai, Shanghai , China

Abstract

SPR biosensor with OLED and nano-grating for HBV LAMP product detection is reported. Directional emissions by grating-coupler match the resonant condition of SP modes. Concentration changes result in color shift at specific angle. Real time detection of virus load down to 5 copies/25 ul can be achieved in 30 minutes. Surface plasmon Resonant (SPR) biosensor has been used for quantitative measurement of molecular interactions for its advantages of high sensitivity, label-free and real-time detection. In this paper, we report recent efforts on further enhancement of SPR biosensors by the heterogeneous integration of organic electroluminescence light source and nano-grating structure for the feasibility study on the fast and high sensitivity detection of HBV isothermal amplification products, Mg₂P₂O₇. We demonstrated the surface plasmon coupled through hybrid nano-grating structure has highly directional emissions corresponding to the resonant condition of surface plasmon modes on the Au/air interface and controllable plasmonics band-gap by pitch modulation. SPGCE resulted in color change from yellowish green to orange at a certain viewing angle, when contacting glucose with concentration increasing from 10 to 40%.

Citation Download Citation

Chii-Wann Lin, Jun-Haw Lee, Nan-Fu Chiu, Szu-Yuan Lee, Kou-Chen Liu, Feng-Yu Tsai, Chia-Yu Yen, and Chun-Nan Lee "Hybrid nano plasmonics for integrated biosensor", Proc. SPIE 7634, Optical Sensors and Biophotonics, 76340O (30 November 2009); https://doi.org/10.1117/12.853214

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