Influence of Gauss parameter to biological compact disc sensor

WeiLi An; Chen Han; Feng Ying; Liu Long

doi:10.1117/12.866105

12 October 2010 Influence of Gauss parameter to biological compact disc sensor

WeiLi An, Chen Han, Feng Ying, Liu Long

Proceedings Volume 7659, 5th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Smart Structures and Materials in Manufacturing and Testing; 76590Y (2010) https://doi.org/10.1117/12.866105
Event: 5th International Symposium on Advanced Optical Manufacturing and Testing Technologies, 2010, Dalian, China

Abstract

Influence of illuminating beam Gauss parameter to Biological Compact Disc Sensor (BioCD) is presented in this paper. BioCD is a sensitive Interferometry detection platform to detect bimolecular immobilized on the surface of a spinning disk. Interferometry has the advantage of higher photon fluxes than conventional fluorescence detection and consequently shorter detection time. It allows high speed detection of optical path length changes down to sub-nanometer scales with high repeatability. The influences of illuminating beam Gauss parameter to detection sensitivity were simulated. Simulation result showed that Gauss parameter increase will reduce detection sensitivity. But if there is a pinhole filter in optical system Gauss parameter influence could be ignored. This also will be help to Suppression influence of lens aberration, so improve BioCD detection sensitivity.

Citation Download Citation

WeiLi An, Chen Han, Feng Ying, and Liu Long "Influence of Gauss parameter to biological compact disc sensor", Proc. SPIE 7659, 5th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Smart Structures and Materials in Manufacturing and Testing, 76590Y (12 October 2010); https://doi.org/10.1117/12.866105

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