Optical properties measurement of laser coagulated tissues with double integrating sphere and inverse Monte Carlo technique in the wavelength range from 350 to 2100 nm

Norihiro Honda; Takuya Nanjo; Katsunori Ishii; Kunio Awazu

doi:10.1117/12.907704

6 March 2012 Optical properties measurement of laser coagulated tissues with double integrating sphere and inverse Monte Carlo technique in the wavelength range from 350 to 2100 nm

Norihiro Honda, Takuya Nanjo, Katsunori Ishii, Kunio Awazu

Author Affiliations +

Proceedings Volume 8221, Optical Interactions with Tissue and Cells XXIII; 82211F (2012) https://doi.org/10.1117/12.907704
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

In laser medicine, the accurate knowledge about the optical properties (absorption coefficient; μ_a, scattering coefficient; μ_s, anisotropy factor; g) of laser irradiated tissues is important for the prediction of light propagation in tissues, since the efficacy of laser treatment depends on the photon propagation within the irradiated tissues. Thus, it is likely that the optical properties of tissues at near-ultraviolet, visible and near-infrared wavelengths will be more important due to more biomedical applications of lasers will be developed. For improvement of the laser induced thermotherapy, the optical property change during laser treatment should be considered in the wide wavelength range. For estimation of the optical properties of the biological tissues, the optical properties measurement system with a double integrating sphere setup and an inverse Monte Carlo technique was developed. The optical properties of chicken muscle tissue were measured in the native state and after laser coagulation using the optical properties measurement system in the wavelength range from 350 to 2100 nm. A CO₂ laser was used for laser coagulation. After laser coagulation, the reduced scattering coefficient of the tissue increased. And, the optical penetration depth decreased. For improvement of the treatment depth during laser coagulation, a quantitative procedure using the treated tissue optical properties for determination of the irradiation power density following light penetration decrease might be important in clinic.

Citation Download Citation

Norihiro Honda, Takuya Nanjo, Katsunori Ishii, and Kunio Awazu "Optical properties measurement of laser coagulated tissues with double integrating sphere and inverse Monte Carlo technique in the wavelength range from 350 to 2100 nm", Proc. SPIE 8221, Optical Interactions with Tissue and Cells XXIII, 82211F (6 March 2012); https://doi.org/10.1117/12.907704

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available