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An enzyme-based amperometric glucose sensor comprising a cylindrical hydrogen peroxide electrode with oxygen permeable walls and a glucose permeable tip is developed. The sensor has minimal oxygen dependency, low sensitivity to stirring and extended catalytic activity in vitro. The sensor monitored blood glucose levels reasonably well over two-day to three-day periods. However, long term blood exposures (two weeks) diminished the sensor sensitivity for glucose measurements.
Sohrab Mansouri andClinton S Vulu
"Catheter-Type Enzyme Sensor For Glucose Determination", Proc. SPIE 0904, Microsensors and Catheter-Based Imaging Technology, (8 April 1988); https://doi.org/10.1117/12.945226
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Sohrab Mansouri, Clinton S Vulu, "Catheter-Type Enzyme Sensor For Glucose Determination," Proc. SPIE 0904, Microsensors and Catheter-Based Imaging Technology, (8 April 1988); https://doi.org/10.1117/12.945226