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7 March 2022 Evaluation of squamous cell carcinoma surgical margins using two-photon fluorescence microscopy
Chi Huang, Vincent D. Ching-Roa, Sherrif F. Ibrahim, Michael G. Giacomelli
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Proceedings Volume PC11934, Photonics in Dermatology and Plastic Surgery 2022; PC119340D (2022) https://doi.org/10.1117/12.2608414
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
We perform micron-level co-registration of two-photon fluorescence microscopy (TPFM) images with en face frozen section analysis (FSA) histology. We demonstrate that TPFM has excellent sensitivity and specificity for evaluating squamous cell carcinoma (SCC) on surgical margins.
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Chi Huang, Vincent D. Ching-Roa, Sherrif F. Ibrahim, and Michael G. Giacomelli "Evaluation of squamous cell carcinoma surgical margins using two-photon fluorescence microscopy", Proc. SPIE PC11934, Photonics in Dermatology and Plastic Surgery 2022, PC119340D (7 March 2022); https://doi.org/10.1117/12.2608414
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KEYWORDS
Two photon excitation microscopy
Mohs surgery
Silicon photomultipliers
Skin cancer
Tissues
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