Linear and nonlinear effects on enhanced bacterial inactivation using a femtosecond pulsed laser

Marin Saiga; Kazuhiko Misawa

doi:10.1117/12.2609487

7 March 2022 Linear and nonlinear effects on enhanced bacterial inactivation using a femtosecond pulsed laser

Marin Saiga, Kazuhiko Misawa

Proceedings Volume PC11939, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2022; PC1193904 (2022) https://doi.org/10.1117/12.2609487
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

In our previous study, we found that femtosecond pulsed laser can inactivate bacteria more effectively than continuous wave light with UV-C irradiation. We hypothesized that the mechanism of enhanced bacterial inactivation by femtosecond pulsed laser is caused by a nonlinear optical effect due to the high peak intensity. In this experiment, we performed an experiment to compare the bacterial inactivation as the irradiation intensity was varied. This comparative experiment revealed, in the case of UV-C irradiation, that bacterial inactivation effect was the same regardless of the peak intensity and a nonlinear effect of bacterial inactivation does not be confirmed.

Conference Presentation

Citation Download Citation

Marin Saiga and Kazuhiko Misawa "Linear and nonlinear effects on enhanced bacterial inactivation using a femtosecond pulsed laser", Proc. SPIE PC11939, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2022, PC1193904 (7 March 2022); https://doi.org/10.1117/12.2609487

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