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In this research, we demonstrated a CNN-based DOPU estimation algorithm without polarization-sensitive OCT signals. The CNN was trained with pairs of retinal OCT (input) and DOPU (teaching) images. The recall and precision of RPE abnormal appearances between true DOPU and synthesized DOPU of pathological eyes were calculated. For normal eyes, the grader evaluated the soundness of the RPE appearance for true DOPU and synthesized DOPU. The recalls are relatively good (0.74-0.95), while the precisions highly depend on the types of abnormalities (0.37-0.98). Five RPE abnormalities are found in synthesized DOPU within 25 synthesized DOPU B-scans while there is no abnormality in the true DOPU.
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