Hinnerk Schulz-Hildebrandthttps://orcid.org/0000-0003-4389-9151,1 Oscar M. Caravaca Mora,2 Alejandro E. Ortega,3 Ashwin Panikkar,3 Edward C. Farewell,3 Guillermo J Tearney3,1
1Harvard Medical School (United States) 2Massachusetts General Hospital, Harvard Medical School (United States) 3Massachusetts General Hospital (United States)
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We have developed a new µOCT tethered Capsule Endomicroscopy imaging system for the diagnosis of Inflammatory bowel disease and Gastrointestinal cancer with micrometer resolution. The capsule we built measures 30 mm in length and 11 mm in diameter. By employing an optical design that incorporates the mirror tunnel design, we achieved a lateral resolution of less than 4 µm across a depth of field of 450 µm. The spectrometer we designed provides a resolution of 1.8 µm over a 4 mm imaging range, with an A-scan rate of up to 300 kHz. Imaging performance is demonstrated by beam profiling and imaging esophagus ex vivo.
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Hinnerk Schulz-Hildebrandt, Oscar M. Caravaca Mora, Alejandro E. Ortega, Ashwin Panikkar, Edward C. Farewell, Guillermo J Tearney, "Micro-optical coherence tomography capsule for sedation-free esophagus imaging," Proc. SPIE PC12820, Endoscopic Microscopy XIX, PC128200B (13 March 2024); https://doi.org/10.1117/12.3002695