Visually-evoked retinal blood vessel dilation in the human optic nerve head evaluated with a combined OCT+ERG system

Khushmeet K. Dhaliwal; James Simmons; Yadushan Thurairasa; Alex Wong; Chris Hudson; Nadine Furtado; Tom Wright; Brian Ballios; Kostadinka Bizheva

doi:10.1117/12.3001795

13 March 2024 Visually-evoked retinal blood vessel dilation in the human optic nerve head evaluated with a combined OCT+ERG system

Khushmeet K. Dhaliwal, James Simmons, Yadushan Thurairasa, Alex Wong, Chris Hudson, Nadine Furtado, Tom Wright, Brian Ballios, Kostadinka Bizheva

Author Affiliations +

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC1283003 (2024) https://doi.org/10.1117/12.3001795
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Visually-evoked retinal neuronal simulation-induced transient vasodilation of retinal blood vessels is referred to as neurovascular coupling. Both systemic diseases such as Diabetes and high blood pressure, as well as potentially blinding retinal diseases such as Glaucoma have been shown to damage the elasticity of the blood vessels’ walls. In this study, a research-grade, high-resolution OCT system is combined with a commercial electroretinography (ERG) system to investigate flicker-stimulus-induced transient vasodilation in retinal blood vessels around the Optic Nerve Head and study neurovascular coupling in the human retina.

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Khushmeet K. Dhaliwal, James Simmons, Yadushan Thurairasa, Alex Wong, Chris Hudson, Nadine Furtado, Tom Wright, Brian Ballios, and Kostadinka Bizheva "Visually-evoked retinal blood vessel dilation in the human optic nerve head evaluated with a combined OCT+ERG system", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283003 (13 March 2024); https://doi.org/10.1117/12.3001795

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