Pre-transplantation assessment of human lungs using polarization-sensitive optical coherence tomography

Feng Yan; Ebenezer Raj Selvarai Mercyshalinie; Qinghao Zhang; Chen Wang; Zhongxin Yu; Kar-Ming Fung; Qinggong Tang

doi:10.1117/12.3001984

13 March 2024 Pre-transplantation assessment of human lungs using polarization-sensitive optical coherence tomography

Feng Yan, Ebenezer Raj Selvarai Mercyshalinie, Qinghao Zhang, Chen Wang, Zhongxin Yu, Kar-Ming Fung, Qinggong Tang

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC128301U (2024) https://doi.org/10.1117/12.3001984
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Lung transplantation is the last therapy option for patients with advanced lung diseases but the shortage of donor lungs currently is a large challenge. We used a polarization-sensitive optical coherence tomography (PS-OCT) system to obtain the distribution and quantification of alveolus and fibrous tissues. Our results showed that the distribution of alveolus and fibrosis was various at different locations on the lung. PS-OCT was able to provide effective quantifications of the alveolus density and size, and the fibrous tissues verified by the histology results. PS-OCT could serve as a promising tool for assessing the quality of donor lungs.

Conference Presentation

Citation Download Citation

Feng Yan, Ebenezer Raj Selvarai Mercyshalinie, Qinghao Zhang, Chen Wang, Zhongxin Yu, Kar-Ming Fung, and Qinggong Tang "Pre-transplantation assessment of human lungs using polarization-sensitive optical coherence tomography", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128301U (13 March 2024); https://doi.org/10.1117/12.3001984

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available