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Laser-induced cavitation accompanies laser surgery in cells and transparent tissues and its engineering can improve surgical results. To elucidate the underlying mechanisms, plasma-mediated shock wave formation and bubble dynamics are investigated by stroboscopic and high-speed photography with ultrahigh spatiotemporal resolution. We developed a novel light source for speckle-free illumination at exposure times < 100 ps that is based on amplified spontaneous emission (ASE) and lasing in a femtosecond-laser-pumped Rhodamine dye cell. The contributions from ASE and lasing and their influence on pulse duration, divergence and coherence are investigated, and the emission characteristics are optimized for high repetition rates.
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Sebastian Freidank, Lei Fu, Xiao-Xuan Liang, Alfred Vogel, Norbert Linz, "Development of a novel light source with sub 100-ps temporal resolution for the investigation of laser-induced cavitation," Proc. SPIE PC12840, Optical Interactions with Tissue and Cells XXXV, PC1284003 (13 March 2024); https://doi.org/10.1117/12.3000880