Quantum-optimal bioimaging based on multi-pass reimaging

Mark A. Kasevich; Shaun Burd; Joshua Reynolds; Jerry Yen

doi:10.1117/12.3005189

13 March 2024 Quantum-optimal bioimaging based on multi-pass reimaging

Mark A. Kasevich, Shaun Burd, Joshua Reynolds, Jerry Yen

Proceedings Volume PC12863, Quantum Effects and Measurement Techniques in Biology and Biophotonics; PC128630F (2024) https://doi.org/10.1117/12.3005189
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We present progress towards demonstrating multi-passed stimulated Raman scattering microscopy and multi-passed transmission electron microscopy. A multi-pass microscope interrogates a sample multiple times in a cyclical and deterministic fashion. This can lead to a metrological advantage for imaging weak scatterers. The enhanced sensitivity can yield a significant reduction in damage imparted to biological samples or can reduce image acquisition time. The approach compares favorably with imaging techniques using squeezed or entangled probe states, but avoids the technical complexity associated with the production of such states.

Conference Presentation

Citation Download Citation

Mark A. Kasevich, Shaun Burd, Joshua Reynolds, and Jerry Yen "Quantum-optimal bioimaging based on multi-pass reimaging", Proc. SPIE PC12863, Quantum Effects and Measurement Techniques in Biology and Biophotonics, PC128630F (13 March 2024); https://doi.org/10.1117/12.3005189

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