Improving cancer photoimmunotherapy: Integrating targeted nanotechnology, a clinical laser microendoscopy, and fluorescence-guided intervention

Huang-Chiao Huang; Barry J. Liang; Sumiao Pang; Robert Perttila; Chen-Hua Ma; Payal Srivastava; Brandon Gaitan; Aaron Sorrin; Nada Fadul; Idrisa Rahmana; Zoe Ylöniemi; Dana M. Roque; Tayyaba Hasan; Petteri Uusimaa

doi:10.1117/12.3012419

19 June 2024 Improving cancer photoimmunotherapy: Integrating targeted nanotechnology, a clinical laser microendoscopy, and fluorescence-guided intervention

Huang-Chiao Huang, Barry J. Liang, Sumiao Pang, Robert Perttila, Chen-Hua Ma, Payal Srivastava, Brandon Gaitan, Aaron Sorrin, Nada Fadul, Idrisa Rahmana, Zoe Ylöniemi, Dana M. Roque, Tayyaba Hasan, Petteri Uusimaa

Author Affiliations +

Proceedings Volume PC13009, Clinical Biophotonics III; PC1300909 (2024) https://doi.org/10.1117/12.3012419
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

Advanced-stage ovarian cancer becomes extremely challenging to treat effectively using current surgical and chemotherapy methods due to factors such as peritoneal metastasis, incomplete resection, and drug resistance. While photoimmunotherapy is emerging as a promising option for unresectable metastases, its full potential often goes unrealized due to varying treatment outcomes. This research effort aims to enhance the reliability, safety, and effectiveness of photoimmunotherapy for peritoneal metastases by combining targeted nanotechnology, fluorescence-guided intervention, and a state-of-the-art medical laser system.

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Huang-Chiao Huang, Barry J. Liang, Sumiao Pang, Robert Perttila, Chen-Hua Ma, Payal Srivastava, Brandon Gaitan, Aaron Sorrin, Nada Fadul, Idrisa Rahmana, Zoe Ylöniemi, Dana M. Roque, Tayyaba Hasan, and Petteri Uusimaa "Improving cancer photoimmunotherapy: Integrating targeted nanotechnology, a clinical laser microendoscopy, and fluorescence-guided intervention", Proc. SPIE PC13009, Clinical Biophotonics III, PC1300909 (19 June 2024); https://doi.org/10.1117/12.3012419

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