Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system

Hirokazu Atsumori; Masashi Kiguchi; Takusige Katura; Tsukasa Funane; Akiko Obata; Hiroki Sato; Takaaki Manaka; Mitumasa Iwamoto; Atsushi Maki; Hideaki Koizumi; Kisou Kubota

doi:10.1117/1.3462996

1 July 2010 Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system

Hirokazu Atsumori, Masashi Kiguchi, Takusige Katura, Tsukasa Funane, Akiko Obata, Hiroki Sato, Takaaki Manaka, Mitumasa Iwamoto, Atsushi Maki, Hideaki Koizumi, Kisou Kubota

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Journal of Biomedical Optics, Vol. 15, Issue 4, 046002 (July 2010). https://doi.org/10.1117/1.3462996

Abstract

Optical topography (OT) based on near-infrared spectroscopy is a noninvasive technique for mapping the relative concentration changes in oxygenated and deoxygenated hemoglobin (oxy- and deoxy-Hb, respectively) in the human cerebral cortex. In our previous study, we developed a small and light wearable optical topography (WOT) system that covers the entire forehead for monitoring prefrontal activation. In the present study, we examine whether the WOT system is applicable to OT measurement while walking, which has been difficult with conventional OT systems. We conduct OT measurements while subjects perform an attention-demanding (AD) task of balancing a ping-pong ball on a small card while walking. The measured time course and power spectra of the relative concentration changes in oxy- and deoxy-Hb show that the step-related changes in the oxy- and deoxy-Hb signals are negligible compared to the task-related changes. Statistical assessment of the task-related changes in the oxy-Hb signals show that the dorsolateral prefrontal cortex and rostral prefrontal area are significantly activated during the AD task. These results suggest that our functional imaging technique with the WOT system is applicable to OT measurement while walking, and will be a powerful tool for evaluating brain activation in a natural environment.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Hirokazu Atsumori, Masashi Kiguchi, Takusige Katura, Tsukasa Funane, Akiko Obata, Hiroki Sato, Takaaki Manaka, Mitumasa Iwamoto, Atsushi Maki, Hideaki Koizumi, and Kisou Kubota "Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system," Journal of Biomedical Optics 15(4), 046002 (1 July 2010). https://doi.org/10.1117/1.3462996

Published: 1 July 2010

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