Speckle reduction in optical coherence tomography images using tissue viscoelasticity

Brendan F. Kennedy; Andrea Curatolo; David D. Sampson; Timothy R. Hillman; Christobel Saunders

doi:10.1117/1.3548239

1 February 2011 Speckle reduction in optical coherence tomography images using tissue viscoelasticity

Brendan F. Kennedy, Andrea Curatolo, David D. Sampson, Timothy R. Hillman, Christobel Saunders

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Journal of Biomedical Optics, Vol. 16, Issue 2, 020506 (February 2011). https://doi.org/10.1117/1.3548239

Abstract

We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution.

©(2011) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Brendan F. Kennedy, Andrea Curatolo, David D. Sampson, Timothy R. Hillman, and Christobel Saunders "Speckle reduction in optical coherence tomography images using tissue viscoelasticity," Journal of Biomedical Optics 16(2), 020506 (1 February 2011). https://doi.org/10.1117/1.3548239

Published: 1 February 2011

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