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5 July 2012 Gold nanoisland structures integrated in a lab-on-a-chip for plasmonic detection of bovine growth hormone
Jayan Ozhikandathil, Simona Badilescu, Muthukumaran Packirisamy
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Journal of Biomedical Optics, Vol. 17, Issue 7, 077001 (July 2012). https://doi.org/10.1117/1.JBO.17.7.077001
Abstract
Three-dimensional gold nanostructures fabricated through a novel convective assembly method are treated thermally to obtain a nanoisland morphology. The new structure is proved to be adequate for the detection of bovine growth hormone, by using an immunoassay method based on the localized surface plasmon resonance band of gold. The nanoisland structures are integrated into a microfluidic device and the spectral measurements are carried out by introducing the device directly in the light beam of a ultraviolet-visible spectrophotometer. The principal motivation for this work is the need for a simple and rapid method of detection of hormone levels in milk and milk products.
© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2012/$25.00 © 2012 SPIE
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Jayan Ozhikandathil, Simona Badilescu, and Muthukumaran Packirisamy "Gold nanoisland structures integrated in a lab-on-a-chip for plasmonic detection of bovine growth hormone," Journal of Biomedical Optics 17(7), 077001 (5 July 2012). https://doi.org/10.1117/1.JBO.17.7.077001
Published: 5 July 2012
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Cited by 28 scholarly publications and 1 patent.
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KEYWORDS
Gold
Nanoparticles
Nanostructures
Microfluidics
Refractive index
Annealing
Nanolithography
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