Confocal microlaparoscope for imaging the fallopian tube

Tzu-Yu Wu; Andrew R. Rouse; Setsuko K. Chambers; Kenneth D. Hatch; Arthur F. Gmitro

doi:10.1117/1.JBO.19.11.116010

20 November 2014 Confocal microlaparoscope for imaging the fallopian tube

Tzu-Yu Wu, Andrew R. Rouse, Setsuko K. Chambers, Kenneth D. Hatch, Arthur F. Gmitro

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Journal of Biomedical Optics, Vol. 19, Issue 11, 116010 (November 2014). https://doi.org/10.1117/1.JBO.19.11.116010

Abstract

Recent evidence suggests that ovarian cancer can originate in the fallopian tube. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. A rigid confocal microlaparoscope system designed to image the epithelial surface of the ovary in vivo was previously reported. A new confocal microlaparoscope with an articulating distal tip has been developed to enable in vivo access to human fallopian tubes. The new microlaparoscope is compatible with 5-mm trocars and includes a 2.2-mm-diameter articulating distal tip consisting of a bare fiber bundle and an automated dye delivery system for fluorescence confocal imaging. This small articulating device should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube. Ex vivo images of animal tissue and human fallopian tube using the new articulating device are presented along with in vivo imaging results using the rigid confocal microlaparoscope system.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Tzu-Yu Wu, Andrew R. Rouse, Setsuko K. Chambers, Kenneth D. Hatch, and Arthur F. Gmitro "Confocal microlaparoscope for imaging the fallopian tube," Journal of Biomedical Optics 19(11), 116010 (20 November 2014). https://doi.org/10.1117/1.JBO.19.11.116010

Published: 20 November 2014

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