Intraoperative hyperspectral determination of human tissue properties

Eric Larry Wisotzky; Florian Cornelius Uecker; Philipp Arens; Steffen Dommerich; Anna Hilsmann; Peter Eisert

doi:10.1117/1.JBO.23.9.091409

9 May 2018 Intraoperative hyperspectral determination of human tissue properties

Eric Larry Wisotzky, Florian Cornelius Uecker, Philipp Arens, Steffen Dommerich, Anna Hilsmann, Peter Eisert

Author Affiliations +

Journal of Biomedical Optics, Vol. 23, Issue 9, 091409 (May 2018). https://doi.org/10.1117/1.JBO.23.9.091409

Abstract

We address the automatic differentiation of human tissue using multispectral imaging with promising potential for automatic visualization during surgery. Currently, tissue types have to be continuously differentiated based on the surgeon’s knowledge only. Further, automatic methods based on optical in vivo properties of human tissue do not yet exist, as these properties have not been sufficiently examined. To overcome this, we developed a hyperspectral camera setup to monitor the different optical behavior of tissue types in vivo. The aim of this work is to collect and analyze these behaviors to open up optical opportunities during surgery. Our setup uses a digital camera and several bandpass filters in front of the light source to illuminate different tissue types with 16 specific wavelength ranges. We analyzed the different intensities of eight healthy tissue types over the visible spectrum (400 to 700 nm). Using our setup and sophisticated postprocessing in order to handle motion during capturing, we are able to find tissue characteristics not visible for the human eye to differentiate tissue types in the 16-dimensional wavelength domain. Our analysis shows that this approach has the potential to support the surgeon’s decisions during treatment.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Eric Larry Wisotzky, Florian Cornelius Uecker, Philipp Arens, Steffen Dommerich, Anna Hilsmann, and Peter Eisert "Intraoperative hyperspectral determination of human tissue properties," Journal of Biomedical Optics 23(9), 091409 (9 May 2018). https://doi.org/10.1117/1.JBO.23.9.091409

Received: 29 January 2018; Accepted: 23 April 2018; Published: 9 May 2018

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KEYWORDS

Tissues

Tissue optics

Surgery

Optical filters

Cameras

Bone

Connective tissue

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