Open Access
27 September 2019 Impact of velocity gradient in Poiseuille flow on the statistics of coherent radiation scattered by flowing Brownian particles in optical coherence tomography
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Abstract

A closed-form expression is obtained for the temporal correlation function of the scattered radiation detected in optical coherence tomography (OCT), taking into account the flow velocity gradient across the OCT detection volume in the suspension of flowing Brownian particles. The analytical approach we use includes both the laser beam and wavefront curvature radii changing over the depth. Also, we compare our results with a previously obtained theoretical model, partially an empirical approach. Our findings suggest the importance of the flow velocity gradient for accurate measurements of flow velocity vector, particle diffusivity, shear-induced diffusion, and potentially other OCT applications.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
Ivan Popov, Andrew S. Weatherbee, and Alex Vitkin "Impact of velocity gradient in Poiseuille flow on the statistics of coherent radiation scattered by flowing Brownian particles in optical coherence tomography," Journal of Biomedical Optics 24(9), 097001 (27 September 2019). https://doi.org/10.1117/1.JBO.24.9.097001
Received: 25 January 2019; Accepted: 23 August 2019; Published: 27 September 2019
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Cited by 1 scholarly publication.
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KEYWORDS
Optical coherence tomography

Doppler effect

Particles

Correlation function

Capillaries

Diffusion

Gaussian beams

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