Mr. Md. Mahmud-Ul-Hasan Profile

Md. Mahmud-Ul-Hasan

at imec

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Publications (12)

Proceedings Article | 10 April 2023 Presentation

Photoacoustic imaging using an optomechanical ultrasound sensor for future applications in breast cancer imaging

Hilde Jans, Cedric Pieters, Deep Bera, Grim Keulemans, Roelof Jansen, Veronique Rochus, Jon Kjellman, Hasan Mahmud-Ul-Hasan, Xavier Rottenberg

Proceedings Volume 12468, 1246810 (2023) https://doi.org/10.1117/12.2654145

KEYWORDS: Breast cancer, Sensors, Photoacoustic imaging, Ultrasonography, Mammography, Tumors, Tissue optics, Photoacoustic spectroscopy, Diagnostics, Breast

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Proceedings Article | 3 March 2022 Presentation + Paper

Photoacoustic raster scan imaging using an optomechanical ultrasound sensor in silicon photonics

Cedric Pieters, Wouter Westerveld, Hasan Mahmud-Ul-Hasan, Simone Severi, Jon Kjellman, Roelof Jansen, Veronique Rochus, Xavier Rottenberg

Proceedings Volume 11960, 1196017 (2022) https://doi.org/10.1117/12.2607501

KEYWORDS: Sensors, Photoacoustic imaging, Photoacoustic tomography, Optomechanical design, Silicon photonics

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Proceedings Article | 9 December 2021 Paper

Sensitive optomechanical ultrasound sensor in a silicon photonic chip towards single-shot photoacoustic imaging with an ultrasound sensor matrix

Cedric Pieters, Wouter Westerveld, Md. Mahmud-Ul-Hasan, Simone Severi, Rami Shnaiderman, Vasilis Ntziachristos, Margo Billen, Jon Kjellman, Roelof Jansen, Veronique Rochus, Xavier Rottenberg

Proceedings Volume 11923, 119230Q (2021) https://doi.org/10.1117/12.2615909

KEYWORDS: Sensors, Ultrasonography, Silicon photonics, Photoacoustic imaging, Waveguides, Silicon, Photonics, Mendelevium, Medical imaging

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Proceedings Article | 5 March 2021 Presentation

Silicon photonic opto-mechanical ultrasound sensor for photoacoustic imaging

Wouter Westerveld, Md. Mahmud-Ul-Hasan, Rami Shnaiderman, Cedric Pieters, Vasilis Ntziachristos, Roelof Jansen, Xavier Rottenberg, Simone Severi, Veronique Rochus

Proceedings Volume 11642, 1164223 (2021) https://doi.org/10.1117/12.2577599

KEYWORDS: Sensors, Ultrasonography, Silicon photonics, Waveguides, Photoacoustic imaging, Image sensors, Wafer-level optics, Optical multiplexing, Resonators, Optical fibers

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Proceedings Article | 5 March 2021 Presentation

Optomechanical ultrasound sensors in silicon photonics

Wouter Westerveld, Md. Mahmud-Ul-Hasan, Cedric Pieters, Roelof Jansen, Simone Severi, Veronique Rochus, Xavier Rottenberg

Proceedings Volume 11691, 116910H (2021) https://doi.org/10.1117/12.2576672

KEYWORDS: Sensors, Ultrasonography, Silicon photonics, Waveguides, Photoacoustic imaging, Waveguide sensors, Tomography, Refractive index, Photoacoustic spectroscopy, Optical fibers

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Proceedings Article | 2 April 2020 Open Access

Chip-based super-resolution structured illumination microscopy (Conference Presentation)

Qingzhong Deng, Ongun Arisev, Dmitry Kouznetsov, MD Mahmud Ul Hasan, Pieter Neutens, Zhenxiang Luo, Seungkyu Ha, Kris Covens, Rita Vos, Pol Van Dorpe, Niels Verellen

Proceedings Volume 11364, 113641F (2020) https://doi.org/10.1117/12.2557750

KEYWORDS: Microscopy, Super resolution, Luminescence, Photonic integrated circuits, Waveguides, Light wave propagation, Biology, Medicine, Diffraction, Structured light

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Proceedings Article | 15 March 2018 Presentation

Integrated metasurface photonics for miniature flow cytometry (Conference Presentation)

Niels Verellen, Dries Vercruysse, Veronique Rochus, Bert Du Bois, Alexandra Dusa, Sarp Kerman, Md. Mahmud-Ul-Hasan, Pol Van Dorpe, Xavier Rottenberg, Liesbet Lagae

Proceedings Volume 10506, 105060X (2018) https://doi.org/10.1117/12.2287116

KEYWORDS: Photonics, Optical components, Flow cytometry, Silicon, Diffraction gratings, Life sciences, Visible radiation, Waveguides, Integrated optics, Integrated photonics

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Proceedings Article | 15 March 2018 Presentation

Angular dependence of bulk fluorescence noise in supercritical angle fluorescence (Conference Presentation)

Finub James Shirley, Pieter Neutens, Rita Vos, Md. Mahmud-Ul-Hasan, Niels Verellen, Pol Van Dorpe

Proceedings Volume 10506, 105060P (2018) https://doi.org/10.1117/12.2289951

KEYWORDS: Luminescence, Near field, Interfaces, Biosensors, Fluorescence spectroscopy, Spectroscopy, Waveguides, Molecules, Biosensing, Microscopy

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Proceedings Article | 24 April 2017 Presentation

On-chip near field fluorescence excitation and detection with nanophotonic waveguides for enhanced surface sensitivity (Conference Presentation)

Md. Mahmud-Ul-Hasan, Pieter Neutens, Liesbet Lagae, Pol Van Dorpe

Proceedings Volume 10077, 1007702 (2017) https://doi.org/10.1117/12.2250963

KEYWORDS: Biological and chemical sensing, Chemistry, Near field, Waveguides, Molecules, Luminescence, Biosensing, Data modeling, Fluorescence spectroscopy, Nanophotonics

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Proceedings Article | 26 July 2016 Presentation

Fluorescence excitation and detection on a chip using nanophotonic waveguides (Conference Presentation)

Md. Mahmud-Ul-Hasan, Pieter Neutens, Liesbet Lagae, Pol van Dorpe

Proceedings Volume 9884, 988405 (2016) https://doi.org/10.1117/12.2227918

KEYWORDS: Waveguides, Fluorescence spectroscopy, Biosensing, Nanophotonics, Near field, Waveguide modes

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Often, in bio-sensing applications rely on fluorescence as the transduction mechanism. The emission from the fluorescently labeled molecules is detected and quantified to obtain the concentration. Most current techniques, such as ELISA, FISH, next generation DNA sequencing and others need one or several washing steps to remove the unreacted fluorescent molecules to reduce the background noise. To address that problem, we propose an integrated nano-photonic solution for on-chip fluorescence detection. The proposed platform is tailored for bio-sensing applications and has the potential to analyze bio-molecular interactions down to the single molecule level. The technology is based on near-field excitation and collection using PECVD Silicon Nitride (SiN) nano-photonic rib waveguides. SiN provides the combination of high-index-contrast and compatibility with CMOS processing technology, and unlike silicon, Silicon Nitride does not absorb in the visible wavelength window. The evanescent tail of the used SiN waveguide mode extends from 80 nm to 200 nm above the waveguide surface depending on the waveguide geometry, cladding material and excitation wavelength. Hereby, the evanescent field of the waveguide mode excites a very thin layer of molecules near to the surface. The subsequent emission from the excited fluorophore is collected in the near field by coupling to another waveguide. The coupling strength mainly depends on the distance between the waveguide and fluorophore. This way, both the excitation and collection efficiency have an exponential dependency on the distance between the molecule and waveguide surface. Therefore, exciting and collecting fluorescence using photonic waveguides improves the separation between the surface bound fluorescence signal from the bulk background noise, paving the way for wash free bio-sensing. Wash-free assays allow to examine the bio-molecular interactions in real time and simplify the sample/liquid handling system. Next to bulk fluorescence, autofluorescence generated in the SiN waveguide is another large contributor to noise. In the proposed design, the two separate single mode waveguides we use to excite fluorophores and collect the emission, are placed orthogonally in a cross configuration. The orthogonal placement of two Transverse Electric (TE) mode waveguides makes sure that the auto-fluorescence generated in the excitation waveguide is not coupled to the emission waveguide. As a result, we observe an improved signal-to-noise-ratio (SNR) which is a very critical parameter towards single molecule detection. In this talk, I will talk about the design, fabrication and characterization of the proposed cross-configured waveguide based fluorescence detection platform. Experimental results to quantify the excitation efficiency, collection efficiency and SNR will be discussed. A comparison will be shown between the Finite Difference Time Domain (FDTD) simulation and experimental results.

Proceedings Article | 13 May 2016 Paper

On-chip fluorescence excitation and collection by focusing grating couplers

Sarp Kerman, Dries Vercruysse, Tom Claes, Mahmud Ul Hasan, Pieter Neutens, Vignesh Mukund, Xavier Rottenberg, Liesbet Lagae, Pol Van Dorpe

Proceedings Volume 9891, 98911L (2016) https://doi.org/10.1117/12.2227740

KEYWORDS: Luminescence, Waveguides, Silicon, Fluorescence spectroscopy, Microscopes, Microfluidics, Photonics, Diffraction gratings, Silicon photonics, Integrated optics, Etching, Finite-difference time-domain method, Visible radiation, Optical design, Optical fiber cables

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Proceedings Article | 1 May 2014 Paper

Characterization of PECVD silicon nitride photonic components at 532 and 900 nm wavelength

P. Neutens, A. Subramanian, M. Ul Hasan, C. Chen, R. Jansen, T. Claes, X. Rottenberg, B. Du Bois, K. Leyssens, P. Helin, S. Severi, A. Dhakal, F. Peyskens, L. Lagae, P. Deshpande, R. Baets, P. Van Dorpe

Proceedings Volume 9133, 91331F (2014) https://doi.org/10.1117/12.2052119

KEYWORDS: Waveguides, Oxides, Wave propagation, Cladding, Silicon, Silicon photonics, Plasma enhanced chemical vapor deposition, Resonators, Electron beam lithography, Semiconducting wafers

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Showing 5 of 12 publications

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