KEYWORDS: 3D modeling, Data modeling, Monte Carlo methods, Absorption, Spherical lenses, Optical properties, Bioluminescence, Photon transport, Diffusion, 3D image processing
A three dimensional (3D) photon transport model has been developed based on the frequency domain simplified
spherical harmonics approximation (SPN) to the Radiative Transport Equation. Based on preliminary Monte Carlo
studies, it is shown that for problems exhibiting strong absorption, the solutions using the 7th order SPN model (N = 7) are
significantly more accurate than those from a standard Diffusion (SP1) based solver. This advance is of particular
interest in the field of bioluminescent imaging where the peak emission of light emitting molecular markers are closer to
the visible range (500 - 650 nm) corresponding to strong absorption due to hemoglobin.
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