Imaging techniques with subdiffraction-limited spatial resolutions are highly desired for a deeper understanding of subcellular systems. Optical imaging enables high resolution under 200 nm while the visible light penetration depth is limited to merely 2 mm. Ultrasound images achieve two orders of magnitude lower resolutions but can penetrate two orders of magnitude deeper into a medium than optical images. This work combines the strengths of optical and acoustic imaging techniques through AuNP-based metasurfaces utilizing the photoacoustic effect that gold exhibits. Our novel imaging technique can simultaneously achieve high resolution and deep penetration depths without any destruction of media.
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