As a traditional Chinese medicine practice, cupping therapy has been widely used for thousands of years to promote blood circulation and release symptoms of some diseases. The actual effect, however, has been debatable due to the lack of scientific evidence. Aiming to objectively assess the treatment effect, in this study we introduce optical-resolution photoacoutic microscopy to monitor the structural and functional changes of microenvironment parameters pre- and post-cupping through facial cups. Whilst further investigation is in demand, this pilot study provides a new imaging perspective to understand the mechanism and evaluate the effect of cupping therapy.
A biomimetic photoacoustic nano-probe is synthesized for enhanced the diagnostic accuracy of hepatocellular carcinoma. It is prepared by using erythrocyte membrane to coat the gold nano-star which shows significant photothermal effect. This probe can escape the clearance by mononuclear phagocytic system because of the inherent proteins on the surface of the erythrocyte membrane. Such an ability to evade immune clearance allows a longer circulation time in vivo, promotes probe enrichment at tumor site, and improves signal-to-noise ratio. Sequentially, it is used as an agent of non-invasive photothermal treatment for tumor and experimentally perform a longer life span of mice.
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