Unspecified Yuyao Zhang Profile

Yuyao Zhang

at Fujian Normal University

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Proceedings Article | 15 November 2022 Paper

Tissue photothermal effect based on photoacoustic temperature feedback control

Yuyao Zhang, Xuke Chu, Wenliang Cao, Shulian Wu, Huiyun Lin, Zhifang Li

Proceedings Volume 12448, 124480U (2022) https://doi.org/10.1117/12.2638164

KEYWORDS: Temperature metrology, Tissues, Photoacoustic spectroscopy, Pulsed laser operation, Laser tissue interaction, Photothermal effect, Feedback signals, Feedback control

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hotothermal therapy (PTT) is an alternative to surgery, which is commonly used to treat tumors in intracavitary organs. PTT involves heating the diseased tissue with radiation energy, resulting in tumor necrosis. In order to improve the safety and effectiveness of PT, it is necessary to monitor the tissue temperature in real time and regulate the laser power during PTT. Photoacoustic imaging (PAI) is a non-invasive and non-ionizing imaging method with high resolution and high accuracy. Due to the dependence of the thermal expansion coefficient on temperature, the Grüneisen parameter is linearly proportional to temperature, and the variation of the amplitude of the photoacoustic signal is related to the variation of the Grüneisen parameter. In this study, we propose a system for laser dose regulation with photoacoustic signal temperature feedback based on PID algorithm. The pulsed laser is irradiated on the sample surface, the ultrasonic probe receives the photoacoustic signal generated by the sample, and the photoacoustic signal is collected by the oscilloscope and transmitted to the computer, which generates the corresponding command to the heating laser according to the signal and changes the output power of the heating laser. The experimental results show that this method can effectively control the photothermal damage range.

Proceedings Article | 15 November 2022 Paper

Electromagnetic radiation study of skin sweat duct model

Zhenqian Li, Bin Liu, Wangbiao Li, Yuyao Zhang, Zhifang Li

Proceedings Volume 12448, 124480Z (2022) https://doi.org/10.1117/12.2638355

KEYWORDS: Skin, Antennas, Electromagnetic radiation, Optical coherence tomography, Radiation effects

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Terahertz waves are increasingly used in fields such as information and communication technology, homeland security, and biomedical engineering. Optical Coherence Tomography (OCT) is a non-invasive, high-resolution imaging technique that can image within a depth of 1mm under the skin, and it has the characteristics of fast imaging speed and high detection sensitivity. Using OCT technology to study human skin, it was found that the human skin sweat ducts are helical structures. When the sweat ducts of the helical structure are filled with sweat composed of conductive electrolytes, combined with the morphological and dielectric properties of the skin, the sweat ducts can act as low Q-factor helical antennas and have electromagnetic effects in the Sub-Terahertz band. In this study, based on the morphological structure of sweat ducts in the skin, we established a basic sweat duct equivalent model, which consists of spiral sweat ducts and three skin layers (stratum corneum, epidermis, and dermis). In this work, we investigate the frequency points of the stronger radiation of the sweat duct model at different frequencies and compare the effects of the turning direction of the helical sweat duct and changing the length of the sweat duct on its radiation variation at specific frequencies. The results show that there are significant differences in the magnitude and direction of planar radiation for different lengths of sweat ducts, and the differences in the turning direction of the helical sweat ducts also affect the angle of sweat duct radiation. The research on the electromagnetic radiation characteristics of sweat tubes in this study is of great guidance to the IC design research of human skin sweat tubes.

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