Optical Transduction Of Chemoreceptive Events: Towards A Fiber-Optic Biosensor

Ulrich J. Krull; R. Stephen Brown; A. Safarzadeh-Amiri

doi:10.1117/12.945254

21 June 1988 Optical Transduction Of Chemoreceptive Events: Towards A Fiber-Optic Biosensor

Ulrich J. Krull, R. Stephen Brown, A. Safarzadeh-Amiri

Proceedings Volume 0906, Optical Fibers in Medicine III; (1988) https://doi.org/10.1117/12.945254
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

Phosphatidyl choline-cholesterol and stearic acid monolayers and multilayers were deposited onto borosilicate glass, quartz and crystalline silicon surfaces by transfer from the air-water interface of a Langmuir-Blodgett trough. Contact angle, ellipsometric, X-ray photoelectron and fluorescence measurements provided characterization of phospholipid monolayers on hydrated or alkylated silicate surfaces. A fluorescent lipid film supported on a quartz optical fiber demonstrated the feasibility of preparation of an evanescent-wave based intrinsic optrode. Further development of intrinsic biosensors based on lipid membrane structures is described in terms of optical conduction of lipid multilayer wave guides, and new membrane-soluble fluorescence probes such as trans-4-dimethylamino-4'-(1-oxobutyl)stilbene.

Citation Download Citation

Ulrich J. Krull, R. Stephen Brown, and A. Safarzadeh-Amiri "Optical Transduction Of Chemoreceptive Events: Towards A Fiber-Optic Biosensor", Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); https://doi.org/10.1117/12.945254

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