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Here, I will describe my lab’s efforts to improve medicine contrast via customized plasmonic contrast agents and imaging including in vitro and in vivo applications. I will discuss the medical needs and limitations of current technology and then describe how colloidal materials can solve these fundamental limitations. The first example will be imaging and quantitation of reactive oxygen species implicated in a variety of inflammatory disease. The second will be colorimetric sensing of proteases with implications in surveillance of infectious diseases including SARS viruses. I will close with an overview of more fundamental work creating nanoparticles with exotic yet exquisitely controlled shapes and hybrid structures.
Jesse V. Jokerst
"Plasmonic sensing and imaging of disease (Conference Presentation)", Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC1239503 (17 March 2023); https://doi.org/10.1117/12.2651503
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Jesse V. Jokerst, "Plasmonic sensing and imaging of disease (Conference Presentation)," Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC1239503 (17 March 2023); https://doi.org/10.1117/12.2651503