Optoretinography serves as an effective biomarker for light-evoked retinal activity owing to its sensitive, objective, and precise localization of retinal function and dysfunction. We developed a coarse-scale optoretinography instrument based on a line-scan spectral domain OCT. We demonstrate its ability to acquire robust and repeatable ORG signals rapidly over a 5° field of view in a single acquisition, without adaptive optics. The high repeatability, good agreement with cellular-scale ORGs, and non-AO operation are of promise for its widespread clinical application to retinal diseases such as AMD and inherited retinal degenerations.
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