Clinical utility of all fiber-based polarization sensitive optical coherence tomography

Athira B.S.; Aishwarya Shukla; Irl B. Hirsch; Stephanie Kim; Nina Lu; Ruikang K. Wang

doi:10.1117/12.3004849

13 March 2024 Clinical utility of all fiber-based polarization sensitive optical coherence tomography

Athira B.S., Aishwarya Shukla, Irl B. Hirsch, Stephanie Kim, Nina Lu, Ruikang K. Wang

Proceedings Volume PC12816, Photonics in Dermatology and Plastic Surgery 2024; PC128160I (2024) https://doi.org/10.1117/12.3004849
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

In clinical dermatology, understanding collagen remodeling and reorganization are most important. Collagen provides the support matrix underpinning healthy skin and is key to preserving skin firmness and elasticity. Any issue with collagen deposition and deviation would affect the appearance in skin. In this regard, an ability to monitor the morphological changes in collagen organizations along with vascular morphology may improve our understanding in its pathophysiology and, ultimately, prevent these abnormal conditions. In this effort, we developed an advanced single input in house-built polarization-sensitive optical coherence tomography (PSOCT) device to directly visualize collagen organization within skin in vivo in various dermatological conditions like lipoatrophy, Necrobiosis lipoidica diabeticorum, and surgical scars to show the clinical utility of the system.

Conference Presentation

Citation Download Citation

Athira B.S., Aishwarya Shukla, Irl B. Hirsch, Stephanie Kim, Nina Lu, and Ruikang K. Wang "Clinical utility of all fiber-based polarization sensitive optical coherence tomography", Proc. SPIE PC12816, Photonics in Dermatology and Plastic Surgery 2024, PC128160I (13 March 2024); https://doi.org/10.1117/12.3004849

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