Artificial intelligence (AI) training courses often require prerequisites such as calculus or statistics. It is hence challenging to design and develop an introductory AI course for students of secondary education. This research intends to develop a medical AI course, provide high school students with an overview of deep learning applications in medical image analysis, and inspire them to pursue careers in the field of medical AI. We designed a 20-hour course, including lectures and two hands-on projects based on medical image classification. The proposed courses provided medical AI disciplines and built up their knowledge from basic to advanced levels. During the ten-day online courses, all the students were fully engaged and gave us positive feedback. The students endeavored to complete the experimental study in training, testing, and hypothesis of medical images application in the course. Their performance exceeded all expectations, for they did further analysis by tuning different hyperparameters. We designed a course evaluation form, which suggested that the students found it essential and expected to interact with the instructors. The results indicate that combining lectures with hands-on sessions would lead to evidently better achievement in terms of high school students’ medical AI knowledge and positive attitudes while addressing real-world problems in the projects. Through this innovative education model, high school students regained their enthusiasm and were encouraged to cultivate their medical AI skills through self-learning while finishing the project. We conclude that this course could be successfully applied to interdisciplinary education in high school.
Respiratory auscultation can help healthcare professionals detect abnormal respiratory conditions if adventitious lung sounds are heard. The state-of-the-art artificial intelligence technologies based on deep learning show great potential in the development of automated respiratory sound analysis. To train a deep learning-based model, a huge number of accurate labels of normal breath sounds and adventitious sounds are needed. In this paper, we demonstrate the work of developing a respiratory sound labeling software to help annotators identify and label the inhalation, exhalation, and adventitious respiratory sound more accurately and quickly. Our labeling software integrates six features from MATLAB Audio Labeler, and one commercial audio editor, RX7. As of October, 2019, we have labeled 9,765 15- second-long audio files of breathing lung sounds, and accrued 34,095 inhalation labels,18,349 exhalation labels, 13,883 continuous adventitious sounds (CASs) labels and 15,606 discontinuous adventitious sounds (DASs) labels, which are significantly larger than previously published studies. The trained convolutional recurrent neural networks based on these labels showed good performance with F1-scores of 86.0% on inhalation event detection, 51.6% on CASs event detection and 71.4% on DASs event detection. In conclusion, our results show that our proposed respiratory sound labeling software could easily pre-define a label, perform one-click labeling, and overall facilitate the process of accurately labeling. This software helps develop deep learning-based models that require a huge amount of labeled acoustic data.
Acute kidney injury (AKI) is associated with increased morbidity and mortality in intensive care units (ICU). The sudden episode of kidney failure may lead to end-stage renal disease (ESRD) or deaths, and has been related to significantly increasing costs of ICU admissions and treatments. Early prediction of AKI inpatient mortality will help decision-making, and benefit resource allocation in ICU. Therefore, it is crucial to develop an early warning system for AKI prediction. We aimed to create a more comprehensive predictive model for 1-year AKI mortality. A cohort of 2,247 patients with AKI was assembled, of which the in-hospital mortality was 36.67%. Longitudinal data of each patient were collected from the Medical Information Mart for Intensive Care III (MIMIC-III) dataset. An interpretable XGBoost risk model was developed and validated by 10-fold cross validation. Model predictors included 11 routinely collected AKI-related laboratory measurements, 8 complications of AKI, and demographic data. An artificial neural network (ANN) model was also developed in parallel for comparison. The XGBoost model demonstrated an area under the receiver-operating characteristic curve (AUC) of 0.83, which was superior to ANN (AUC = 0.79). Our model was able to predict mortality of AKI in ICU with high accuracy. Our model can predict 1-year AKI mortality. Furthermore, it had great potential for identifying at-risk patients in ICU. These findings indicated that our approach might offer opportunities for better resource utilization and better administration of AKI.
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