Dr. Ilko K. Ilev Profile

Dr. Ilko K. Ilev

at US Food and Drug Administration

SPIE Involvement:

Conference Program Committee | Author

Publications (34)

SPIE Journal Paper | 20 July 2022 Open Access

Evaluation of standardized performance test methods for biomedical Raman spectroscopy (Erratum)

Andrew Fales, Ilko Ilev, T. Joshua Pfefer

JBO, Vol. 27, Issue 07, 079801, (July 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.079801

KEYWORDS: Raman spectroscopy, Biomedical optics, Silver

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SPIE Journal Paper | 28 October 2021 Open Access

Evaluation of standardized performance test methods for biomedical Raman spectroscopy

Andrew Fales, Ilko Ilev, T. Joshua Pfefer

JBO, Vol. 27, Issue 07, 074705, (October 2021) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074705

KEYWORDS: Raman spectroscopy, Calibration, Spectrometers, Standards development, Biomedical optics, Sensors, Particles, Spectrographs, Signal to noise ratio, Lamps

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SPIE Journal Paper | 22 June 2019 Open Access

Experimental investigation of parameters influencing plasmonic nanoparticle-mediated bubble generation with nanosecond laser pulses

Andrew Fales, William Vogt, Keith Wear, T. Joshua Pfefer, Ilko Ilev

JBO, Vol. 24, Issue 06, 065003, (June 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.6.065003

KEYWORDS: Nanorods, Gold, Particles, Laser damage threshold, Plasmonics, Pulsed laser operation, Nanoparticles, Acoustics, Absorption, Transmission electron microscopy

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SPIE Journal Paper | 18 June 2018 Open Access

Noncontact method for sensing thickness and refractive index of intraocular lens implants using a self-calibrating dual-confocal laser caliper

Do-Hyun Kim, Robert James, Don Calogero, Ilko Ilev

JBO, Vol. 23, Issue 06, 067004, (June 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.6.067004

KEYWORDS: Refractive index, Confocal microscopy, Objectives, Calibration, Microscopes, Reflection, Signal detection, Fiber optics, Sensors, Mirrors

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Proceedings Article | 23 February 2018 Paper

Size-dependent thresholds for melting and nanobubble generation using pulsed-laser irradiated gold nanoparticles

Andrew Fales, William Vogt, Keith Wear, Joshua Pfefer, Ilko Ilev

Proceedings Volume 10509, 105090C (2018) https://doi.org/10.1117/12.2290114

KEYWORDS: Nanoparticles, Gold, Laser damage threshold, Pulsed laser operation, Particles, Acoustics, Scattering, Transmission electron microscopy, Laser scattering, Nd:YAG lasers

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Proceedings Article | 19 April 2017 Presentation

A tribute to Dr. Ron W. Waynant (Conference Presentation)

Israel Gannot, Ilko Ilev, Juanita Anders, Jin Kang

Proceedings Volume 10058, 1005802 (2017) https://doi.org/10.1117/12.2255003

KEYWORDS: Health sciences, Current controlled current source, Specialty optical fibers, Ultraviolet radiation, Vacuum ultraviolet, Fiber optics, Free electron lasers, Optical fibers, Sensors, Medical diagnostics

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Proceedings Article | 3 May 2016 Presentation

Fiber-optic Fourier transform infrared (FO-FTIR) spectroscopy for detecting endotoxin contamination in ophthalmic viscosurgical devices (OVDS) (Conference Presentation)

Moinuddin Hassan, Ilko Ilev

Proceedings Volume 9702, 970204 (2016) https://doi.org/10.1117/12.2219746

KEYWORDS: Contamination, Fiber optics, FT-IR spectroscopy, Spectroscopes, Surgery, Eye, Tissues, Infrared spectroscopy, Spectroscopy, Mid-IR

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Proceedings Article | 26 April 2016 Open Access

Advanced biosensing methodologies developed for evaluating performance quality and safety of emerging biophotonics technologies and medical devices (Conference Presentation)

Ilko Ilev, Bennett Walker, William Calhoun, Moinuddin Hassan

Proceedings Volume 9702, 97020O (2016) https://doi.org/10.1117/12.2220083

KEYWORDS: Biomedical optics, Safety, Medical device development, Biosensing, Laser applications, Fiber optics, Laser safety, Standards development, Imaging spectroscopy, Coherence imaging

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Proceedings Article | 26 April 2016 Presentation

Effect of laser polarization and pulse energy on therapeutic, femtosecond laser-induced second harmonic generation in corneal tissue (Conference Presentation)

William Calhoun, Ilko Ilev

Proceedings Volume 9693, 96931B (2016) https://doi.org/10.1117/12.2216264

KEYWORDS: Second-harmonic generation, Laser vision correction, Polarization, Pulsed laser operation, Laser therapeutics, Laser tissue interaction, Tissue optics, Femtosecond phenomena, Harmonic generation, Surgery

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SPIE Journal Paper | 9 May 2014 Open Access

Assessing the effect of laser beam width on quantitative evaluation of optical properties of intraocular lens implants

Bennett Walker, Robert James, Aurin Chakravarty, Don Calogero, Ilko Ilev

JBO, Vol. 19, Issue 05, 055004, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.5.055004

KEYWORDS: Refractor telescopes, Optical properties, Confocal microscopy, Standards development, Optics manufacturing, Tolerancing, Collimation, Laser therapeutics, Fiber optics tests, Fiber optics

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Proceedings Article | 20 February 2014 Paper

Monitoring biofilm attachment on medical devices surfaces using hyperspectral imaging

Hanh Le, Victoria Hitchins, Ilko Ilev, Do-Hyun Kim

Proceedings Volume 8938, 893809 (2014) https://doi.org/10.1117/12.2047867

KEYWORDS: Glasses, Hyperspectral imaging, Luminescence, Medical devices, Reflectivity, Bacteria, Signal detection, Proteins, Lamps, Spectrographs

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SPIE Journal Paper | 16 September 2013 Open Access

Retina-simulating phantom for optical coherence tomography

Jigesh Baxi, William Calhoun, Yasir Sepah, Daniel Hammer, Ilko Ilev, T. Joshua Pfefer, Quan Dong Nguyen, Anant Agrawal

JBO, Vol. 19, Issue 02, 021106, (September 2013) https://doi.org/10.1117/12.10.1117/1.JBO.19.2.021106

KEYWORDS: Optical coherence tomography, Eye, Coating, Tissues, Retina, Eye models, Scattering, Particles, Optical properties, Imaging systems

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Proceedings Article | 26 March 2013 Paper

Quantification of phase retardation in corneal tissues using a femtosecond laser

William Calhoun, Alexander Beylin, Richard Weiblinger, Ilko Ilev

Proceedings Volume 8567, 85672B (2013) https://doi.org/10.1117/12.2005954

KEYWORDS: Cornea, Tissues, Phase measurement, Femtosecond phenomena, Laser therapeutics, Laser development, Laser vision correction, Polarization, Laser ablation, LASIK

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SPIE Journal Paper | 1 December 2011 Open Access

Noncontact common-path Fourier domain optical coherence tomography method for in vitro intraocular lens power measurement

Yong Huang, Don Calogero, Robert James, Ilko Ilev, Jin Kang, Kang Zhang

JBO, Vol. 16, Issue 12, 126005, (December 2011) https://doi.org/10.1117/12.10.1117/1.3660313

KEYWORDS: Optical coherence tomography, Refractor telescopes, Distortion, In vitro testing, Fluctuations and noise, Standards development, Refraction, Refractive index, Optical properties, Interfaces

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Proceedings Article | 17 February 2011 Paper

A thickness measurement method for biological samples using lensed-fiber sensors

Do-Hyun Kim, Ilko Ilev, Young-Geun Han

Proceedings Volume 7894, 789416 (2011) https://doi.org/10.1117/12.881640

KEYWORDS: Confocal microscopy, Lenses, Microscopes, Objectives, Sensors, Fiber optics sensors, Refractive index, Fiber optics, Head, Glasses

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Proceedings Article | 24 February 2010 Paper

Analysis of some substantial collimating lens functions in fiber optic confocal microscopy

Do-Hyun Kim, Ilko Ilev

Proceedings Volume 7559, 75590E (2010) https://doi.org/10.1117/12.843689

KEYWORDS: Confocal microscopy, Microscopes, Collimation, Fiber optics, Optical fibers, Objectives, Signal to noise ratio, Fiber optics tests, Light sources, Single mode fibers

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Proceedings Article | 24 February 2010 Paper

Suppression of modal noise in a multimode fiber optic delivery output from an ultra-broadband supercontinuum light source

Do-Hyun Kim, Karl-Friedrich Klein, Ilko Ilev

Proceedings Volume 7559, 75590U (2010) https://doi.org/10.1117/12.846973

KEYWORDS: Light sources, Single mode fibers, Lenses, Multimode fibers, Supercontinuum sources, Objectives, Light, Optical fibers, Photonic crystal fibers, Sensors

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Proceedings Article | 23 February 2009 Paper

Effects of optical irradiation parameters on safe peripheral nerve stimulation with infrared light

Elizabeth Katz, Do-Hyun Kim, Ilko Ilev, Victor Krauthamer

Proceedings Volume 7180, 71800P (2009) https://doi.org/10.1117/12.816718

KEYWORDS: Nerve, Pulsed laser operation, Tissue optics, Laser tissue interaction, Laser damage threshold, Safety, Electrodes, Semiconductor lasers, Er:YAG lasers, Laser irradiation

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Proceedings Article | 21 February 2009 Paper

Advanced confocal fiber-optic imaging and sensing approaches

Do-Hyun Kim, Jin Kang, Ilko Ilev

Proceedings Volume 7173, 71730B (2009) https://doi.org/10.1117/12.816537

KEYWORDS: Confocal microscopy, Microscopes, Upconversion, Fiber optics, Light sources, Signal to noise ratio, Image resolution, Objectives, Fiber optics sensors, Optical fibers

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SPIE Journal Paper | 1 September 2005

Pulse dispersion in hollow optical waveguides

M. Ben-David, Ilko Ilev, Ronald Waynant, Israel Gannot

OE, Vol. 44, Issue 09, 095001, (September 2005) https://doi.org/10.1117/12.10.1117/1.2042967

KEYWORDS: Dispersion, Waveguides, Hollow waveguides, Wave propagation, Pulsed laser operation, Surface roughness, Beam shaping, Optical engineering, Signal attenuation, Dielectrics

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Proceedings Article | 10 September 2004 Paper

Light sources and their role in laser therapy

Ronald Waynant, Ilko Ilev

Proceedings Volume 5610, (2004) https://doi.org/10.1117/12.584390

KEYWORDS: Laser therapeutics, Oxygen, Light emitting diodes, Optical filters, Light sources, Skin, Gas lasers, Control systems, Light, Laser tissue interaction

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Proceedings Article | 13 July 2004 Paper

Are ultrashort x-ray pulses likely to be less carcinogenic?

Ronald Waynant, Ilko Ilev, Kunal Mitra

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.528234

KEYWORDS: X-rays, Oxygen, Femtosecond phenomena, X-ray imaging, Tumors, Tissues, Ultrafast phenomena, 3D image processing, Breast, Image resolution

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Proceedings Article | 10 June 2004 Paper

A fiber optic approach for in vivo minimally invasive study of tissue optical properties

Ilko Ilev, Ronald Waynant, Kimberly Byrnes, Juanita Anders

Proceedings Volume 5317, (2004) https://doi.org/10.1117/12.529159

KEYWORDS: Tissue optics, Blood, In vivo imaging, Fiber optics, Tissues, Optical properties, Light sources, Laser sources, Connective tissue, Biomedical optics

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Proceedings Article | 12 September 2003 Paper

A concept for early cancer detection and therapy

Ronald Waynant, Ilko Ilev, Kunal Mitra

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.476526

KEYWORDS: Tumors, X-rays, Cancer, Tissue optics, Biopsy, Tissues, Image resolution, X-ray imaging, Laser scattering, Femtosecond phenomena

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Proceedings Article | 1 July 2003 Paper

Rare-earth oxide: aluminum oxide glasses for midrange IR devices

Richard Weber, Ronald Waynant, Ilko Ilev, Thomas Key, Paul Nordine

Proceedings Volume 4957, (2003) https://doi.org/10.1117/12.485589

KEYWORDS: Glasses, Optical fibers, Erbium, Oxides, Silica, Luminescence, Lanthanum, Liquids, Mid-IR, Infrared radiation

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Proceedings Article | 1 July 2003 Paper

Combined fiber optic confocal microscopy for noninvasive optical sensing

Ilko Ilev, Ronald Waynant, Erik Gorman, Reggie Luedtke, Kimberly Byrnes, Juanita Anders

Proceedings Volume 4957, (2003) https://doi.org/10.1117/12.488652

KEYWORDS: Sensors, Confocal microscopy, Fiber optics sensors, Fiber optics, Refractive index, Transmittance, Microscopes, Oxygen, Fiber optics tests, Optical sensing

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Proceedings Article | 24 July 2002 Paper

On-the-spot laser therapy using a smart tissue-activated fiber probe

Ilko Ilev, Ronald Waynant

Proceedings Volume 4608, (2002) https://doi.org/10.1117/12.437971

KEYWORDS: Laser tissue interaction, Laser therapeutics, Tissues, Fiber lasers, Beam delivery, Natural surfaces, Optical fibers, Radiation effects, Laser optics, Diagnostics

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Proceedings Article | 26 March 2002 Paper

Transmission characteristics of an all-optical-waveguide biomedical system for x-ray delivery

Ronald Waynant, Ilko Ilev, Kunal Mitra, Israel Gannot, Robert Jennings

Proceedings Volume 4616, (2002) https://doi.org/10.1117/12.463803

KEYWORDS: X-rays, Waveguides, Glasses, Reflection, Tumors, Biomedical optics, X-ray optics, Hollow waveguides, Capillaries, Lead

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Proceedings Article | 26 March 2002 Paper

Smart optical fiber probes for precise tissue treatment

Ilko Ilev, Ronald Waynant, Mary Reiter

Proceedings Volume 4616, (2002) https://doi.org/10.1117/12.463817

KEYWORDS: Laser tissue interaction, Tissues, Biomedical optics, Tissue optics, Fiber lasers, Skin, Optical fibers, Natural surfaces, Laser therapeutics, Mid-IR

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Proceedings Article | 4 June 2001 Paper

Evanescent-wave delivery into a precise tissue area using fiber optic probes

Ilko Ilev, Ronald Waynant, Michael Bonaguidi

Proceedings Volume 4253, (2001) https://doi.org/10.1117/12.427918

KEYWORDS: Laser tissue interaction, Infrared lasers, Fiber lasers, Tissues, Laser therapeutics, Fiber optics, Infrared imaging, Infrared radiation, Beam delivery, Thermography

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Proceedings Article | 21 May 2001 Paper

Waveguide delivery of x rays for minimally invasive tumor therapy

Ronald Waynant, Ilko Ilev, Kunal Mitra

Proceedings Volume 4244, (2001) https://doi.org/10.1117/12.427840

KEYWORDS: X-rays, Tumors, Waveguides, Tissues, Hollow waveguides, Tissue optics, X-ray optics, X-ray sources, Photons, Biopsy

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Proceedings Article | 16 April 2001 Paper

High-resolution fiber optic confocal microscope

Ilko Ilev, Ronald Waynant

Proceedings Volume 4261, (2001) https://doi.org/10.1117/12.424531

KEYWORDS: Confocal microscopy, Microscopes, Multimode fibers, Optical fibers, Spatial resolution, Fiber lasers, Fiber optics, Graded index fibers, Signal detection, Objectives

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Proceedings Article | 19 January 2001 Paper

Ultraviolet, visible, and infrared laser delivery using laser-to-fiber coupling via a grazing-incidence-based hollow taper

Ilko Ilev, Ronald Waynant

Proceedings Volume 4158, (2001) https://doi.org/10.1117/12.413782

KEYWORDS: Ultraviolet radiation, Optical fibers, Grazing incidence, Reflectivity, Reflection, Glasses, Infrared lasers, Visible radiation, Fiber lasers, Optical filters

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Proceedings Article | 10 December 1999 Paper

Medical applications of infrared fibers and waveguides

Ronald Waynant, Ilko Ilev, Israel Gannot

Proceedings Volume 3849, (1999) https://doi.org/10.1117/12.372788

KEYWORDS: Waveguides, Optical fibers, Infrared radiation, Tissues, Sapphire, Hollow waveguides, Surgery, Liquids, Chalcogenides, Glasses

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Showing 5 of 34 publications

Conference Committee Involvement (41)

Smart Biomedical and Physiological Sensor Technology XXII

14 April 2025 | Orlando, Florida, United States

Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXV

25 January 2025 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XXI

22 April 2024 | National Harbor, Maryland, United States

Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXIV

27 January 2024 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XX

1 May 2023 | Orlando, Florida, United States

Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXIII

28 January 2023 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XIX

4 April 2022 | Orlando, Florida, United States

Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXII

22 January 2022 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XVIII

12 April 2021 | Online Only, Florida, United States

Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI

6 March 2021 | Online Only, California, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX

1 February 2020 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XVI

15 April 2019 | Baltimore, MD, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIX

2 February 2019 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XV

15 April 2018 | Orlando, FL, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII

27 January 2018 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XIV

9 April 2017 | Anaheim, CA, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII

28 January 2017 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XIII

18 April 2016 | Baltimore, MD, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI

13 February 2016 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XII

23 April 2015 | Baltimore, MD, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV

7 February 2015 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology XI

7 May 2014 | Baltimore, MD, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV

1 February 2014 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology X

1 May 2013 | Baltimore, Maryland, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIII

2 February 2013 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology IX

26 April 2012 | Baltimore, Maryland, United States

Synthesis and Photonics of Nanoscale Materials IX

23 January 2012 | San Francisco, California, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XII

22 January 2012 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technology VIII

28 April 2011 | Orlando, Florida, United States

Synthesis and Photonics of Nanoscale Materials VIII

24 January 2011 | San Francisco, California, United States

Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI

22 January 2011 | San Francisco, California, United States

Smart Biomedical and Physiological Sensor Technologies VII

8 April 2010 | Orlando, Florida, United States

Synthesis and Photonics of Nanoscale Materials VII

27 January 2010 | San Francisco, California, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications X

23 January 2010 | San Francisco, California, United States

Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside

1 October 2009 | Bethesda, Maryland, United States

Smart Biomedical and Physiological Sensor Technology VI

16 April 2009 | Orlando, Florida, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications IX

24 January 2009 | San Jose, California, United States

Synthesis and Photonics of Nanoscale Materials VI

24 January 2008 | San Jose, California, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VIII

19 January 2008 | San Jose, California, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII

20 January 2007 | San Jose, California, United States

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VI

21 January 2006 | San Jose, California, United States

Showing 5 of 41 Conference Committees

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