Surgical site infection is a significant threat to the patient after surgery and is associated with over a third of postoperative deaths. In this work we evaluate spatial frequency domain imaging (SFDI) for clinical use in monitoring wound structural changes and early signs of infection. We use both Monte Carlo and experimental techniques to image embedded vertical wound models. The simulation aids in analyzing heterogeneity between tissues with different optical parameters to detect changes due to infection. The exact resolution of SFDI measurement for scattering and wound width will be discussed.
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