Ms. Laura Newman Profile

Laura Newman

at Mayo Clinic

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 4 April 2022 Poster + Paper

Quantification of cardiac motion using in vivo fiducial markers for beam ablation of cardiac arrhythmias

M. Rettmann, S. Hohmann, H. Konishi, L. Newman, A. Deisher, J. Kruse, K. Merrell, R. Foote, M. Herman, D. Packer

Proceedings Volume 12034, 120342I (2022) https://doi.org/10.1117/12.2613484

KEYWORDS: Computed tomography, Heart, In vivo imaging, Beam delivery, Radiation oncology

Read Abstract +

External beam ablation therapy has the potential to treat cardiac arrhythmias non-invasively by targeting arrhythmogenic myocardial tissue; however, a challenge of treating cardiac tissue with beam ablation therapy is cardiac motion. Currently, cardiac motion is typically compensated by expansion of the target volume which can potentially lead to collateral damage of surrounding healthy tissue. This collateral damage could be minimized by gating the beam delivery to a portion of the cardiac cycle. In prior work, we evaluated cardiac motion using anatomic landmarks in multi-phase cardiac computed tomography volumes of swine hearts across the left atria and ventricles. Other work evaluated left atrial motion using implanted fiducial clips. In the current work, we extend this prior work by quantifying cardiac motion using gold standard implanted fiducial clips across all four chambers of the heart. Cardiac motion varied by chamber, ranging from 2.1 to 7.2 mm in the x direction, 7.2 to 8.1 mm in the y direction, and 3.1 to 9.7 mm in the z direction. In addition, we quantify the reduction in motion if delivery were gated to phases 40% to 90% of the cardiac cycle, which corresponds to treating across 50% of the cardiac cycle. Cardiac motion across 50% of the cardiac cycle ranged from 1.1 to 5.3 mm in the x direction, 4.5 to 5.2 mm in the y direction, and 1.2 to 7.8 mm in the z direction. Percentage reduction in motion for treating during 50% of the cardiac cycle ranged from 18% to 47% in the x direction, 31% to 43% in the y direction, and 11% to 61% in the z direction. These results demonstrate that a substantial improvement in target localization could be achieved by gating the beam to 50% of the cardiac cycle.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years