For fast wavefront correction based on coherence-gated wavefront sensing (CGWS) photon and speckle noise determine how well the wavefront can be corrected and, thus, how much resolution, signal and contrast of multi-photon microscopy can be improved. We investigate numerically the performance of a virtual Shack-Hartmann sensor (vSHS), which can be used to reconstruct the wavefront in CGWS, taking into account photon noise and speckle noise.
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