Dr. Yuriy S. Polyakov Profile

Dr. Yuriy S. Polyakov

at USPolyResearch

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Proceedings Article | 15 June 2007 Paper

Phenomenological analysis of medical time series with regular and stochastic components

Serge Timashev, Yuriy Polyakov

Proceedings Volume 6602, 660210 (2007) https://doi.org/10.1117/12.724571

KEYWORDS: Stochastic processes, Organisms, Fourier transforms, Spectroscopy, Signal attenuation, Transform theory, Chromium, Biological research, Time metrology, Signal generators

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Flicker-Noise Spectroscopy (FNS), a general approach to the extraction and parameterization of resonant and stochastic components contained in medical time series, is presented. The basic idea of FNS is to treat the correlation links present in sequences of different irregularities, such as spikes, "jumps", and discontinuities in derivatives of different orders, on all levels of the spatiotemporal hierarchy of the system under study as main information carriers. The tools to extract and analyze the information are power spectra and difference moments (structural functions), which complement the information of each other. The structural function stochastic component is formed exclusively by "jumps" of the dynamic variable while the power spectrum stochastic component is formed by both spikes and "jumps" on every level of the hierarchy. The information "passport" characteristics that are determined by fitting the derived expressions to the experimental variations for the stochastic components of power spectra and structural functions are interpreted as the correlation times and parameters that describe the rate of "memory loss" on these correlation time intervals for different irregularities. The number of the extracted parameters is determined by the requirements of the problem under study. Application of this approach to the analysis of tremor velocity signals for a Parkinsonian patient is discussed.

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